What are the optimal settings for a high-end machine?

My specs for my desktop should be in my signature, and I have no trouble running Dolphin 3.5 at stock.

I just want to know what settings you guys use for your high-end desktops (and notebooks if they can be considered high-end).
I plan on making lets plays/streams/machinima with OpenBroadcaster. I'm trying to get the best results for this by maxing-out settings that make a difference in terms of quality, without any speeding up/down, or anything else undesired.

I only play Super Smash Bros Brawl.

My current settings for Dolphin, anything underlined I am open to change:

Dual Core: Yes
Idle skip: Yes
Cheats: No
Framelimit: 60 Limit: Yes
CPU Emu Engine: Jit Recompiler
Lock Threads: No
Force NTSC-J: No

Panic Handlers:Yes
On-Screen Messages: Yes (Off when recording)

Audio Engine: HLE (other two stuff up)
LLE thread: No
Dump Audio: No
Audio Backend: Xaudio2
Sample rate:48000

Skip Bios: Yes

Graphics
Backend:Direct3d11
Adapter:GTX570 (can't really change this =p)
Fullsreen res: 768p (1366x768, probably my only bottleneck is my monitor)
V-Sync: NO
Fullscreen: Yes
FPS counter:Yes, No when recording
Auto window: No
Hide mouse: Yes
Log FPS: No
Window on top: No
Render to main: No

Internal Resolution: 4x Native (2560x2112)
AA: NO
Anisotropic Filter: 16x (Thanks to admin89)
Scaled EFB Copy:Yes
Force Texture Filt: Yes
Per-Pixel Light: No

Skip EFB CPU: No
Ignore Format Changes: Yes
EFB:Enable=>Texture
Texture Acc:(Middle)
Ext Frame Buff:Disable
Cache Display: No
Per-Pixel Depth: Disable
OpenCL Texture Dec: No
Enable Fog
Skip dest alpha: No
Openmp texture dec: Yes

No debugging settings
Dump textures: Yes
Dump EFB target: Yes
Free look: Yes (Too fun to disable)
Load custom textures: No
Dump frames: No (use openbroadcaster)
No Misc settings


So what to you guys recommend I change?